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Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone productsThese include urticariapruritusskin rashflushingangioedemavarious GI symptomsabdominal painnauseavomiting and diarrheafeverarthralgiaserum sickness and wheezingHypersensitivity to levothyroxine itself is not known to occur.

If you have an allergy to levothyroxine or any other part of Synthroidlevothyroxine tabletsIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you have any of these health problemsOveractive thyroid glandrecent heart attackor weak adrenal glandIf you have trouble swallowing.

The therapeutic effects of digitalis glycosides may be reduced by levothyroxineSerum digitalis glycoside levels may be decreased when a hypothyroid patient becomes euthyroidnecessitating an increase in the dose of digitalis glycosidessee Table 2

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