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Do not have immunizations/vaccinations without the consent of your doctorAvoid contact with people who have recently received live vaccinessuch as flu vaccine inhaled through the nose

There is a risk of myelosuppressionMonitoring blood counts weekly throughout the duration of therapy should be emphasized to patients taking HYDREAsee WARNINGS AND PRECAUTIONSAdvise patients to report signs and symptoms of infection or bleeding immediatelyAdvise patients that there is a risk of cutaneous vasculitic toxicities and secondary malignancies including leukemia and skin cancerssee WARNINGS AND PRECAUTIONSAdvise females of reproductive potential of the potential risk to a fetus and to inform their healthcare provider of a known or suspected pregnancyAdvise females and males of reproductive potential to use contraception during and after treatment with HYDREAsee WARNINGS AND PRECAUTIONS and Use in Specific PopulationsAdvise patients to inform their healthcare provider if they have received or are planning to receive vaccinations while taking HYDREA as this may result in a severe infectionsee WARNINGS AND PRECAUTIONSAdvise females to discontinue breastfeeding during treatment with HYDREAsee Use in Specific PopulationsPatients with HIV infection should contact their physician for signs and symptoms of pancreatitishepatic eventsand peripheral neuropathysee WARNINGS AND PRECAUTIONSPostirradiation erythema can occur in patients who have received previous irradiation therapysee WARNINGS AND PRECAUTIONS

Washing handsboth yours and your visitorsis the best way to prevent the spread of infectionAvoid large crowds and people who are sicki.ethose who have a coldfever or cough or live with someone with these symptomsWhen working in your yardwear protective clothing including long pants and glovesDo not handle pet wasteKeep all cuts or scratches cleanShower or bath daily and perform frequent mouth careDo not cut cuticles or ingrown nailsYou may wear nail polishbut not fake nailsAsk your oncology care team before scheduling dental appointments or proceduresAsk your oncology care team before youor someone you live withhas any vaccinations.

You can take hydroxyurea with or without foodDo not cut or crush the capsule.

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anything your doctor tells you about hydrea should be followed even if it is different from what is in this leaflet.

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