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Acetylcholinesterase inhibitors may decrease the effectives of prochlorperazineCentrally acting acetylcholinesterase inhibitors may increase the neurotoxic effects of antipsychotic agentsCombining prochlorperazine with alcoholkava kavaCNS depressantsand cannabis may increase the risk of CNS depressant side effectsAntacids may decrease the absorption of prochlorperazineProchlorperazine may cause anticholinergic side effects such as dry mouthconstipationdry eyesdecreased urinary outputand mental confusionCombining agents with similar anticholinergic effects increases the risk of experiencing such adverse eventsProchlorperazine may increase the blood levels of dofetilideTikosynUse of both drugs is not recommendedDeferoxamineDesferalmay increase the risk of experiencing side effects of prochlorperazine treatmentCombination use has resulted in the prolonged loss of consciousnessMetoclopramideReglanmay increase the side effects of antipsychotic agentsCombination use is not recommendedProchlorperazine may increase the CNS depressant effects of orphenadrineNorflexor paraldehydeParalCombination use is not recommendedCombining prochlorperazine and potassium chloride may result in an increase in the ulcerogenic effect of potassium chlorideKlor-ConCombination use is generally not recommendedCombining prochlorperazine with thalidomideThalomidmay increase the risk of experiencing CNS depressant side effectsThis combination is generally not recommended.

Taking antipsychotic medicine in the last 3 months of pregnancy may cause problems in the newbornsuch as withdrawal symptomsbreathing problemsfeeding problemsfussinesstremorsand limp or stiff musclesHoweveryou may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancyIf you become pregnantdo not stop taking Compazine without your doctor’s advice.

There are many reasons for sudden weight gain when there are no changes in diet or exerciseSudden weight gain could be caused.

Althoughthe exact mechanism of phenothiazine antipsychotics is unknownscientists believe that they may work by blocking the action of dopamine in the brainDopamine is a neurotransmitterchemicalthat nerves use to communicate with one anotherPhenothiazine antipsychotics are used when patients do not respond to other antipsychotics.

Rememberkeep this and all other medicines out of the reach of childrennever share your medicines with othersand use this medication only for the indication prescribed.

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