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As symptoms may be associated with prograf whole blood trough concentrations at or above the recommended range, monitor for neurologic symptoms and consider dosage reduction or discontinuation of astagraf xl if neurotoxicity occurs.

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This medication may raise your blood pressureCheck your blood pressure regularly and tell your doctor if the results are highYour doctor may control your blood pressure with medication.

Dosing should be titrated based on clinical assessments of rejection and tolerabilityLower Prograf dosages than the recommended initial dosage may be sufficient as maintenance therapyAdjunct therapy with adrenal corticosteroids is recommended early post-transplant.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administrationwhenever solution and container permit.

While you take PROGRAF you should not receive any live vaccinesLimit the amount of time you spend in sunlight and avoid exposure to ultravioletUVlightsuch as tanning machinesWear protective clothing and use a sunscreen with a high sun protection factorSPF

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