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When fludrocortisone is used in the small dosages recommendedthe glucocorticoid side effects often seen with cortisone and its derivatives are not usually a problemhowever the following untoward effects should be kept in mindparticularly when fludrocortisone is used over a prolonged period of time or in conjunction with cortisone or a similar glucocorticoid.

Other adverse reactions that may occur following the administration of a corticosteroid are necrotizing angiitisthrombophlebitisaggravation or masking of infectionsinsomniasyncopal episodesand anaphylactoid reactions.

BECAUSE OF ITS MARKED EFFECT ON SODIUM RETENTIONTHE USE OF FLUDROCORTISONE ACETATE IN THE TREATMENT OF CONDITIONS OTHER THAN THOSE INDICATED HEREIN IS NOT ADVISED

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