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This medication may slowlyover months to yearscause brown discoloration of the colored portion of the eyeirisIf you are using latanoprost in only one eyeonly that iris may change colorThis color change may be permanent but the long-term effects are uncertainNotify your doctor if this occurs and schedule regular eye exams to monitor it.

If more than one topical ophthalmic drug is being usedthe drugs should be administered at least five5minutes apart.

Studies in man indicate that the peak concentration in the aqueous humour is reached about two hours after topical administrationAfter topical application in monkeyslatanoprost is distributed primarily in the anterior segmentthe conjunctivae and the eyelidsOnly minute quantities of the drug reach the posterior segment.

Use this medication regularly in order to get the most benefit from itRemember to use it at the same time each dayIt is important to continue using latanoprost even if you feel wellMost people with glaucoma or high pressure in the eye do not feel sick.

Eye swellingrednesssevere discomfortcrusting or drainagemay be signs of infection

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based on 5 years clinical experience, increased iris pigmentation has not been shown to have any negative clinical sequelae and xalatan can be continued if iris pigmentation ensues.

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