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Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzymeACEkininase IIAngiotensin II is the principal pressor agent of the renin-angiotensin systemwith effects that include vasoconstrictionstimulation of synthesis and release of aldosteronecardiac stimulationand renal reabsorption of sodiumDiovanvalsartanblocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT 1 receptor in many tissuessuch as vascular smooth muscle and the adrenal glandIts action is therefore independent of the pathways for angiotensin II synthesis.
Those updates may contain important information about the medicine and its use of which you should be aware.
Talk with your doctor if your symptoms do not improve after 4 weeks of treatment.
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though sales of benicar dipped in 2012, it is among the leaders of angiotensin receptor blockers, or arbs, a category that includes novartis nvs diovan.