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The risks of lactic acidosis associated with metformin therapyits symptomsand conditions that predispose to its developmentas noted in the WARNINGS and PRECAUTIONS sectionsshould be explained to patientsPatients should be advised to discontinue Glucovance immediately and promptly notify their health practitioner if unexplained hyperventilationmyalgiamalaiseunusual somnolenceor other nonspecific symptoms occurOnce a patient is stabilized on any dose level of Glucovancegastrointestinal symptomswhich are common during initiation of metformin therapyare unlikely to be drug relatedLater occurrence of gastrointestinal symptoms could be due to lactic acidosis or other serious disease.

Read about diabetic peripheral neuropathy and exercises to manage nerve painLearn how to cope with the symptoms of diabetic.

Limit alcohol while taking this medication because it can increase the risk of developing low blood sugar and lactic acidosisRarelyalcohol can interact with glyburide and cause a serious reactiondisulfiram-like reactionwith symptoms such as facial flushingnauseavomitingdizzinessor stomach painConsult your doctor or pharmacist about using alcohol safely.

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